Eli Lilly and Company (LLY) Stock Research

Eli Lilly is a pharmaceutical company whose GLP-1 diabetes and obesity treatments have become blockbuster franchises.

For the fiscal year ended December 31, 2025, Eli Lilly and Company reported revenue of $65.2B and net income of $20.6B, with operating cash flow of $16.8B. Source: Form 10-K filed February 12, 2026

Reviewed · SEC data as of

Revenue
$65.2B
FY ending 2025-12-31
Net income
$20.6B
FY ending 2025-12-31
Diluted EPS
$22.95
Net margin
31.7%

Reported SEC XBRL figures. Each metric’s period and original filing are listed below.

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About Eli Lilly and

It also develops therapies in oncology, immunology, and neuroscience.

Exchange
NYSE: LLY
Sector
Health Care
SEC industry
Pharmaceutical Preparations (SIC 2834)
Fiscal year end
December 31
Headquarters
Indianapolis, Indiana
Founded
1876

LLY key financials

Reported figures from Eli Lilly and Company's filings, pulled directly from SEC XBRL data rather than a third-party terminal. Each row links to the filing it came from.

MetricValuePeriodSource
Revenue$65.2B2025-01-01 – 2025-12-31SEC filing
Net income$20.6B2025-01-01 – 2025-12-31SEC filing
Operating cash flow$16.8B2025-01-01 – 2025-12-31SEC filing
Diluted EPS$22.952025-01-01 – 2025-12-31SEC filing
Net margin31.7%2025-01-01 – 2025-12-31SEC filing
Shares outstanding943MAs of 2026-02-09SEC filing

Values are as tagged by the issuer in XBRL. Revenue for banks and insurers is net of interest expense where that is the reported line. Fiscal years that do not follow the calendar are shown by their period-end date. No price, market cap, or valuation multiple is shown because Yield Theory does not republish unlicensed market data.

Diluted EPS is the earnings figure behind the price-to-earnings ratio; the P/E multiple compression calculator shows how a change in that multiple moves a share price. Shares outstanding multiplied by the share price gives market capitalization.

What investors should watch in LLY

For Eli Lilly and Company, the most important recurring operating and market variables are:

  • ◆Mounjaro and Zepbound volume, realized pricing, and payer coverage
  • ◆Orforglipron and other pipeline approvals
  • ◆Manufacturing capacity expansion across new U.S. and European sites
  • ◆U.S. drug-pricing agreements, Medicare negotiation, and compounded tirzepatide
  • ◆Patent expiries, including Trulicity in 2027

Key questions for the LLY thesis

Each question starts with what the filings show, then why it matters. None of these is a rating or a forecast.

How concentrated is revenue in incretins?

Mounjaro and Zepbound together accounted for 56% of 2025 revenue, with Mounjaro at $23.0 billion and Zepbound at $13.5 billion, and six products made up 82% of the $65.2 billion total. Item 1A flags this dependence on relatively few products and on three wholesalers; monitor U.S. realized prices, which fell even as volume surged.

What is happening to pricing and access?

The 10-K describes preliminary voluntary agreements with the U.S. government announced in November 2025 to lower Medicaid and certain other prices and to launch new medicines with more balanced pricing across developed nations, plus CVS Caremark's July 2025 removal of Zepbound as a preferred option. Model these against outside-U.S. revenue of $21.7 billion.

Can manufacturing keep up with demand?

Item 1 lists capacity investments at new sites in North Carolina, Wisconsin, Indiana, Virginia, Texas, Alabama, Pennsylvania, Ireland, Germany, and the Netherlands, and Item 1A notes that adding capacity takes years and regulatory approvals. Compare capital spending with the supply commentary and with R&D expense of $13.3 billion.

How durable is the profit margin?

Gross margin reached 83.0% of revenue in 2025 and audited net income was $20.6 billion, or $22.95 per diluted share. Item 1 gives Mounjaro/Zepbound compound patent protection to 2036 in the U.S. but data protection only to 2027, and notes continued mass-compounded incretins; weigh these against orforglipron's regulatory review.

Does LLY's reported profit turn into cash?

Operating cash flow was $16.8B, 0.81 times net income of $20.6B, for the fiscal year ended December 31, 2025.

Cash from operations trailed reported earnings. Working-capital build (receivables, inventory, prepayments) or non-cash gains are the usual reasons; check the cash-flow statement before relying on reported profit.

Form 10-K filed February 12, 2026

How much of LLY's revenue is left as profit?

Net income was 31.7% of revenue for the fiscal year ended December 31, 2025, based on revenue and net income reported for the same period.

Net margin reflects the business model as much as execution, so compare it with companies in the same SEC industry and read the income statement for one-time items before treating it as a run rate.

Form 10-K filed February 12, 2026

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Congressional trading in LLY

PoliticianTrade dateTypeOwnerAmountSource
Dan Newhouse2026-07-10SaleSpouse$1,001 - $15,000Filing #20034998
Michael Rulli2026-07-01SaleSelf$1,001 - $15,000Filing #20035147
Gilbert Cisneros2026-06-10PurchaseSelf$50,001 - $100,000Filing #20034906
Gilbert Cisneros2026-04-14PurchaseSelf$1,001 - $15,000Filing #20034500
Lizzie Fletcher2026-04-08SaleSelf$1,001 - $15,000Filing #20034413
Byron Donalds2026-04-02PurchaseSpouse$1,001 - $15,000Filing #20034478
Byron Donalds2026-04-02PurchaseSelf$1,001 - $15,000Filing #20034478
Alan Armstrong2026-03-27SaleSelf$1,001 - $15,000Filing #fda235b3-bad7-4637-8fa1-053f354d929c
Gilbert Cisneros2026-03-13SaleSelf$1,001 - $15,000Filing #20034285
David Taylor2026-02-26PurchaseSelf$1,001 - $15,000Filing #20034138

All verified LLY congressional disclosures

Congressional disclosures are delayed, range-based records—not real-time signals or proof of motive. See the source-linked tracker for scope and limitations.

LLY — frequently asked questions

What does Eli Lilly and Company do?

Eli Lilly is a pharmaceutical company whose GLP-1 diabetes and obesity treatments have become blockbuster franchises.

What were LLY's latest reported annual revenue and net income?

For the fiscal year ended December 31, 2025, Eli Lilly and Company reported revenue of $65.2B and net income of $20.6B, with operating cash flow of $16.8B. The figures come from Eli Lilly and Company's SEC XBRL filings.

When does Eli Lilly and Company's fiscal year end?

The SEC lists Eli Lilly and Company's fiscal year end as December 31.

Do members of Congress trade LLY?

The current verified House and Senate snapshot contains 66 transaction rows for LLY, each linked to the original filing.

Where is Eli Lilly and Company headquartered?

Eli Lilly and Company is headquartered in Indianapolis, Indiana and was founded in 1876.

Is LLY a good investment?

This page does not rate LLY as a buy or sell. It sets out what Eli Lilly and Company reports, what investors should watch and the questions a thesis has to answer, with links to the SEC filings. It is research, not investment advice.

This page is independent research and educational information, not investment advice or a recommendation to buy or sell any security. Company facts are compiled from public sources. Do your own research.

What do the LLY numbers leave unanswered?

Financials describe the business. The next question is which assumptions an investment thesis depends on. Explore the member reports below for analysis of catalysts, risks, and what would change the view. $39/month or $249/year.

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