Pharmaceutical stocks

Pharmaceutical companies discover, develop, manufacture and sell prescription medicines and vaccines. They earn high margins on patented drugs, so their value depends on how long current products keep exclusivity and whether the pipeline can replace revenue lost when patents expire.

10 covered companies · Reviewed

How pharmaceutical companies make money

Patented branded drugs

Most revenue and profit come from medicines protected by patents and regulatory exclusivity, priced well above manufacturing cost.

Pipeline and licensing

Companies spend heavily on research and buy or license late-stage assets, paying upfront, milestone and royalty amounts.

Generics and animal health

Some group members, such as Viatris in generics and Zoetis in animal health, earn lower-margin or different-cycle revenue.

What drives pharmaceutical stocks

  • ◆Sales growth of the largest products
  • ◆Clinical trial results and regulatory approvals
  • ◆Patent expirations and generic or biosimilar competition
  • ◆Drug-pricing policy, including U.S. Medicare negotiation
  • ◆Acquisitions that add pipeline assets

Key risks

  • ◆Revenue cliffs when major patents expire
  • ◆Trial failures or safety issues
  • ◆Government price controls and rebates
  • ◆Litigation over products and patents

KPIs to track

Revenue by product
Concentration in a few drugs magnifies patent-expiry risk.
R&D as a share of revenue
The ongoing cost of replacing expiring products.
Loss-of-exclusivity schedule
10-K filings list key patent and exclusivity dates.
Late-stage pipeline
Phase 3 programs and pending approvals that could add revenue.

Fiscal calendars in this group

Most large pharmaceutical companies report on a calendar year, which makes annual comparisons straightforward; acquired-research charges can still distort single-year net income.

Fiscal year end (SEC)Companies
December 31ABBV, ABT, LLY, MRK, PFE, REGN, VRTX, VTRS, ZTS
January 3JNJ

Pharmaceutical stocks: company profiles and annual filings

Eli Lilly and Company (LLY)

Company research page

Eli Lilly is a pharmaceutical company whose GLP-1 diabetes and obesity treatments have become blockbuster franchises. It also develops therapies in oncology, immunology, and neuroscience.

Fiscal year end in SEC snapshot
December 31
Annual report period end
2025-12-31
10-K filed 2026-02-12

Abbott Laboratories (ABT)

Abbott operates across medical devices, diagnostics, nutrition, and established pharmaceuticals. Its continuous glucose-monitoring franchise has become a significant growth engine within medical devices.

Fiscal year end in SEC snapshot
December 31
Annual report period end
2025-12-31
10-K filed 2026-02-20

AbbVie Inc. (ABBV)

AbbVie is a biopharmaceutical company known for immunology drugs, aesthetics, and neuroscience treatments. It has worked to replace revenue from its Humira franchise with newer immunology therapies.

Fiscal year end in SEC snapshot
December 31
Annual report period end
2025-12-31
10-K filed 2026-02-20

Johnson & Johnson (JNJ)

Johnson & Johnson develops prescription pharmaceuticals and medical devices following the spin-off of its consumer-health business. Its diversified drug and device pipeline supports a long record of dividend increases.

Fiscal year end in SEC snapshot
January 3
Annual report period end
2025-12-28
10-K filed 2026-02-11

Merck & Co., Inc. (MRK)

Merck is a research-driven pharmaceutical company whose Keytruda immunotherapy is one of the world's top-selling cancer drugs. It also maintains major vaccine and animal-health businesses.

Fiscal year end in SEC snapshot
December 31
Annual report period end
2025-12-31
10-K filed 2026-02-24

Pfizer Inc. (PFE)

Pfizer is a global pharmaceutical company with a broad portfolio spanning vaccines, oncology, and internal medicine. After its pandemic-era surge, it has leaned on acquisitions to rebuild its long-term pipeline.

Fiscal year end in SEC snapshot
December 31
Annual report period end
2025-12-31
10-K filed 2026-02-26

Sources and method

Industry codes and annual filing references come from the SEC submissions snapshot linked to each issuer in our company catalog (snapshot ; newer filings may exist). Only groups with at least three distinct issuers, business descriptions and annual filing links are included. Multiple share classes of one issuer count as one company. This is a coverage directory, not a complete industry census or a ranking of investments.

The industry explanation above is editorial and general; it is not drawn from any single company's filing. Company-specific figures are on each stock page with a link to the filing they come from.

SEC Standard Industrial Classification code list explains the classification system. Read our research methodology or browse all industry directories.

What do the pharmaceutical preparations numbers leave unanswered?

Financials describe the business. The next question is which assumptions an investment thesis depends on. Explore the member reports below for analysis of catalysts, risks, and what would change the view. $39/month or $249/year.

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