Stock research

Vertex Pharmaceuticals Incorporated (VRTX) Stock Research

Vertex Pharmaceuticals develops therapies for cystic fibrosis and other serious diseases including gene-based treatments.

For the fiscal year ended December 31, 2025, Vertex Pharmaceuticals Incorporated reported revenue of $12.0B and net income of $4.0B, with operating cash flow of $3.6B. Source: Form 10-K filed February 13, 2026

SEC data as of

Revenue
$12.0B
FY ending 2025-12-31
Net income
$4.0B
FY ending 2025-12-31
Diluted EPS
$15.32
Net margin
32.9%

Reported SEC XBRL figures. Each metric’s period and original filing are listed below.

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About Vertex Pharmaceuticals

Exchange
NASDAQ: VRTX
Sector
Health Care
SEC industry
Pharmaceutical Preparations (SIC 2834)
Fiscal year end
December 31

VRTX key financials

Reported figures from Vertex Pharmaceuticals Incorporated's filings, pulled directly from SEC XBRL data rather than a third-party terminal. Each row links to the filing it came from.

MetricValuePeriodSource
Revenue$12.0B2025-01-01 – 2025-12-31SEC filing
Net income$4.0B2025-01-01 – 2025-12-31SEC filing
Operating cash flow$3.6B2025-01-01 – 2025-12-31SEC filing
Diluted EPS$15.322025-01-01 – 2025-12-31SEC filing
Net margin32.9%2025-01-01 – 2025-12-31SEC filing
Shares outstanding254MAs of 2026-02-06SEC filing

Values are as tagged by the issuer in XBRL. Revenue for banks and insurers is net of interest expense where that is the reported line. Fiscal years that do not follow the calendar are shown by their period-end date. No price, market cap, or valuation multiple is shown because Yield Theory does not republish unlicensed market data.

Diluted EPS is the earnings figure behind the price-to-earnings ratio; the P/E multiple compression calculator shows how a change in that multiple moves a share price. Shares outstanding multiplied by the share price gives market capitalization.

What investors should watch in VRTX

Vertex Pharmaceuticals Incorporated sits in Health Care. Pharmaceuticals, biotech, medical devices, and managed care — defensive demand paired with binary drug and regulatory catalysts. We have not yet written company-specific drivers for VRTX; the forces that matter most for the sector are:

  • ◆Drug approvals and clinical-trial readouts
  • ◆Medicare and drug-pricing policy
  • ◆Demographics and an aging population
  • ◆GLP-1 and obesity-drug demand

Key questions for the VRTX thesis

Each question starts with what the filings show, then why it matters. None of these is a rating or a forecast.

Does VRTX's reported profit turn into cash?

Operating cash flow was $3.6B, 0.92 times net income of $4.0B, for the fiscal year ended December 31, 2025.

Cash from operations trailed reported earnings. Working-capital build (receivables, inventory, prepayments) or non-cash gains are the usual reasons; check the cash-flow statement before relying on reported profit.

Form 10-K filed February 13, 2026

How much of VRTX's revenue is left as profit?

Net income was 32.9% of revenue for the fiscal year ended December 31, 2025, based on revenue and net income reported for the same period.

Net margin reflects the business model as much as execution, so compare it with companies in the same SEC industry and read the income statement for one-time items before treating it as a run rate.

Form 10-K filed February 13, 2026

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Congressional trading in VRTX

PoliticianTrade dateTypeOwnerAmountSource
David Taylor2026-08-26SaleSelf$1,001 - $15,000Filing #20035392
Alan Armstrong2026-03-27PurchaseSelf$1,001 - $15,000Filing #fda235b3-bad7-4637-8fa1-053f354d929c
David Taylor2026-01-29SaleSelf$1,001 - $15,000Filing #20033916
David Taylor2025-08-07PurchaseSelf$1,001 - $15,000Filing #20030782
Lisa McClain2025-06-11SaleSpouse$1,001 - $15,000Filing #20030891
Lisa McClain2025-06-10SaleSpouse$1,001 - $15,000Filing #20030891
Jefferson Shreve2025-05-12SaleSelf$15,001 - $50,000Filing #20030387
Byron Donalds2025-03-20SaleSelf$1,001 - $15,000Filing #20029092
Byron Donalds2025-03-20SaleSpouse$1,001 - $15,000Filing #20029092
Jefferson Shreve2025-03-13PurchaseSelf$15,001 - $50,000Filing #20029038

All verified VRTX congressional disclosures

Congressional disclosures are delayed, range-based records—not real-time signals or proof of motive. See the source-linked tracker for scope and limitations.

VRTX — frequently asked questions

What does Vertex Pharmaceuticals Incorporated do?

Vertex Pharmaceuticals develops therapies for cystic fibrosis and other serious diseases including gene-based treatments.

What were VRTX's latest reported annual revenue and net income?

For the fiscal year ended December 31, 2025, Vertex Pharmaceuticals Incorporated reported revenue of $12.0B and net income of $4.0B, with operating cash flow of $3.6B. The figures come from Vertex Pharmaceuticals Incorporated's SEC XBRL filings.

When does Vertex Pharmaceuticals Incorporated's fiscal year end?

The SEC lists Vertex Pharmaceuticals Incorporated's fiscal year end as December 31.

Do members of Congress trade VRTX?

The current verified House and Senate snapshot contains 14 transaction rows for VRTX, each linked to the original filing.

Is VRTX a good investment?

This page does not rate VRTX as a buy or sell. It sets out what Vertex Pharmaceuticals Incorporated reports, what investors should watch and the questions a thesis has to answer, with links to the SEC filings. It is research, not investment advice.

This page is independent research and educational information, not investment advice or a recommendation to buy or sell any security. Company facts are compiled from public sources. Do your own research.

What do the VRTX numbers leave unanswered?

Financials describe the business. The next question is which assumptions an investment thesis depends on. Explore the member reports below for analysis of catalysts, risks, and what would change the view. $39/month or $249/year.

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